BAF312 (Siponimod) 162cm

BAF312 (Siponimod) 162cmBAF312 (Siponimod) is a next generation S1P receptor modulator, selective for S1P1 and S1P5 receptors with EC50 of 0. 39 nM and 0. 98 nM, exhibits >1000 fold selectivity over S1P2, S1P3 and S1P4 receptors. Phase 3.

a natural enzyme

Tyrphostin 9 is firstly designed as an EGFR inhibitor with IC50 of 460

and transporters (inhibition <50%)

TG100713 is a pan-PI3K inhibitor against PI3K

is a non-steroidal anti-androgen

lung-selective

AMG 458 is a potent c-Met inhibitor with Ki of 1

CYP1A2 and CYP2C19 with IC50 of 2

Lurasidone is a second-generation antipsychotic agent that exhibits full antagonism at dopamine D2 and serotonin 5-HT2A receptors with binding affinities Ki = 1 nM and Ki = 0

glucogenic amino acid that is primarily found in gelatin and silk fibroin

It is used for the treatment of viral hepatitis

Cytosine is one of the four main bases found in DNA and RNA used in storing and transporting genetic information within a cell