Avapritinib (BLU-285) 12

Avapritinib (BLU-285) 12Avapritinib (BLU 285) is a small molecule kinase inhibitor that potently inhibits PDGFR? D842V mutant activity in vitro (IC50 = 0. 5 nM) and PDGFR? D842V autophosphorylation in the cellular setting (IC50 = 30 nM); also a potent inhibitor of the analogous KIT mutation, D816V in KIT Exon 17 (IC50 = 0. 5 nM).

PHA-793887 is a novel and potent inhibitor of CDK2

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with IC50 of 39 nM

Amprolium chloride is a thiamin antagonist

Cyromazine is a triazine insect growth regulator used as an insecticide and an acaricide

Naquotinib(ASP8273) is an orally available

Theobromine is a xanthine alkaloid widely consumed as stimulants and snacks in coffee and cocoa based foods and most often as part of ingredients in drugs

Purvalanol A is a potent

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it is used as a cough suppressant

Gallic acid